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Chlan L et al. – Recruitment challenges related to the research sites, nursing staff, and research participants faced in the first 2 years of a 4–year multisite clinical trial of a patient–directed music intervention for managing anxiety in the intensive care unit were determined. Strategies to overcome these challenges, and thereby increase enrollment, were devised. Individual strategies, such as timing of screening on a unit, were tailored to each participating site to enhance recruitment for this trial. Other strategies, such as obtaining a waiver for a participant’s signature, were instituted across all participating sites.

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