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Antipsychotic prescribing trends: a review of pharmaco-epidemiological studies
Acta Psychiatrica Scandinavica, 06/30/09
Verdoux H et al. - Considering the growing number of persons from the general population exposed to APs, population studies assessing the risk/benefit ratio of SGAP use in disorders other than psychosis are necessary, particularly in children and adolescents.
Methods- Retrieved original studies that explored AP prescribing trends in general population samples since 2000.
- For each study, we extracted information on sampling method, period, assessment of AP use and corresponding estimates (incidence rates, prevalence rates, pharmacy sales, prescription data) and diagnostic assessment.
- Nearly all studies meeting the inclusion criteria (n = 17) showed an increase in AP prescriptions, mainly because of a dramatic rise in second-generation antipsychotics (SGAP) prescriptions.
- APs are often prescribed for non-psychotic disorders in adults as well as in children and adolescents.
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