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An increased prevalence of fibromyalgia in iron deficiency anemia and thalassemia minor and associated factors
Clinical Rheumatology, 05/09/08

Pamuk GE et al. - Fibromyalgia (FM) was a common finding in patients with iron deficiency anemia (IDA) and thalassemia minor (TM). FM was associated with female sex and history of pica in IDA patients, and not associated with serum hemoglobin and selected iron parameters. The presence of FM in TM had no association with any of the above-mentioned parameters.

Methods

Prevalence of fibromyalgia (FM) in iron deficiency anemia (IDA) and thalassemia minor (TM) pts and associated factors were evaluated
the prevalence of IDA in outpatients with fibromyalgia, and its effect on clinical findings were also investigated
The study included 205 IDA, 40 TM pts and 100 healthy controls
FM was diagnosed according to 1990 ACR criteria
Whole blood count, biochemical tests, and serum iron parameters were determined
Pain, fatigue, and FM Impact Questionnaire (FIQ) functional item scores were assessed in FM subjects
In addition, the prevalence of IDA in FM pts diagnosed at the Rheumatology Outpatient Clinic was determined

Results

Prevalance of FM in IDA (17.6%) and TM (20%) groups were higher than in controls (6%)
Higher percentage of such cases were females, married, and who had a higher percentage of history of pica
Serum hemoglobin and iron parameters did not differ between IDA pts with and w/o FM
IDA was detected in 24.5% of FM pts
FM pts w/o IDA had higher sleep disturbance scores and longer duration of FM

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