Secretory Leukocyte Protease Inhibitor and Helicobacter pylori in the Gastrointestinal Tract of HIV-infected Persons: A Review Chattopadhyay A et al. - Prevalence/incidence of Helicobater pylori (Hp) is reduced in HIV/AIDS. HIV-infection may alter the prevalence/incidence or pathology of Helicobacter pylori (Hp) infection. Secretory leukocyte protease inhibitor (SLPI) is an important broad spectrum innate immunity component that has anti-bacterial and HIV-1 inhibitory activity in different mucosal secretions and possibly in the local mucosal tissue milieu. [more...]