Eliminating the good cholesterol receptor may fight breast cancer Full Text
Removing a lipoprotein receptor known as SR–BI may help protect against breast cancer. SR–BI is a receptor for high–density lipoproteins (HDL) that are commonly referred to as "good cholesterol" because they help transport cholesterol out of the arteries and back to the liver for excretion. Environmental factors, such as diet and obesity, have long been considered risk factors for the high breast cancer incidence in the Western world, and epidemiologic evidence indicates that cancer patients display abnormal levels of cholesterol carrying lipoproteins. However, the role of cholesterol in breast cancer had not yet been specifically examined.