Pediatric chest CT radiation dose reduction: protocol refinement based on noise injection for pulmonary nodule detection accuracy Clinical Imaging, 06/15/2012

Chapman T et al. – Average accuracy for nodule detection in 31 randomly selected cases was 0.87 at 0% dose reduction, 0.90 at 30% reduction, and 0.86 at 60% reduction. The authors observed no clinically relevant difference in acceptability of images or accuracy levels with tested dose reductions to 60%.

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