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At we read 2,000 journals a day so you don’t have to! On a daily basis Nurse Practitioners can find the latest leading medical news articles and peer-reviewed journals ranked, summarized and sorted into over 30 medical specialties. As a member of MDLinx, you will receive daily updates straight to your email inbox FREE OF CHARGE! In addition to being privy to summarized journal articles from all the publishers and the popular press, your membership includes Nurse Practitioner e-newsletters, conference updates, current job listings, paid market research opportunities and continuing medical education (CE) activities.

Below you will find bonus content hand-picked by our senior medical editor, D. Scott Cunningham, MD, Ph.D, as well as clinical pearls derived from our Internal Medicine Review. All this plus more, free with your membership.

Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Changes in adipose tissue depots and metabolic markers following a one-year diet and exercise intervention in overweight and obese patients with type 2 diabetes Diabetes Care, October 23, 2014    Clinical Article

2 Vitamin D level and sustained virologic response to interferon-based antiviral therapy in chronic hepatitis C: A systematic review and meta-analysis Journal of Hepatology, October 23, 2014    Review Article

3 Modified Atkins diet may reduce serum concentrations of antiepileptic drugs Acta Neurologica Scandinavica, October 23, 2014    Clinical Article

4 The relationship between low maternal serum vitamin D levels and glycemic control in gestational diabetes assessed by HbA1c levels: An observational cross-sectional study Full Text BMC Pregnancy and Childbirth, October 23, 2014    Clinical Article

5 Vitamin D levels and bone mineral density: Are LH levels involved in the pathogenesis of bone impairment in hypogonadal men? Full Text Journal of Endocrinological Investigation, October 23, 2014    Clinical Article

6 Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: A prespecified subgroup analysis from the randomised, double-blind, phase 3 ALSYMPCA trial The Lancet Oncology, October 23, 2014    Clinical Article

7 HbA1c as a predictor of diabetes and as an outcome in the diabetes prevention program: a randomized clinical trial Diabetes Care, October 23, 2014    Clinical Article

8 Genomewide association study of nicotine dependence in American populations: Identification of novel risk loci in both African- and European-Americans Biological Psychiatry, October 23, 2014    Clinical Article

9 Neurobiological signatures of anxiety and depression in resting-state fMRI Biological Psychiatry, October 23, 2014    Clinical Article

10 N-methyl-D-aspartate receptor antagonist effects on prefrontal cortical connectivity better model early than chronic schizophrenia Biological Psychiatry, October 23, 2014    Clinical Article

11 Emotion-dependent functional connectivity of the default mode network in adolescent depression Biological Psychiatry, October 23, 2014    Clinical Article

12 Smoking during adolescence as a risk factor for attention problems Biological Psychiatry, October 23, 2014    Clinical Article

13 Neonatal levels of inflammatory markers and later risk of schizophrenia Biological Psychiatry, October 23, 2014    Clinical Article

14 Ivabradine, coronary heart disease, and heart failure: time for reappraisal Current Atherosclerosis Reports, October 23, 2014    Clinical Article

15 Circadian rest–activity rhythms predict future increases in depressive symptoms among community-dwelling older men The American Journal of Geriatric Psychiatry, October 23, 2014    Clinical Article

16 Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction The American Journal of Geriatric Psychiatry, October 23, 2014    Clinical Article

17 The effect of recent bereavement on outcomes in a primary care depression intervention study The American Journal of Geriatric Psychiatry, October 23, 2014    Clinical Article

18 The moderating effect of age on the 12-month prevalence of anxiety and depressive disorders in adults with a lifetime history of cancer The American Journal of Geriatric Psychiatry, October 23, 2014    Clinical Article

19 Bosutinib plus capecitabine for selected advanced solid tumours: results of a phase 1 dose-escalation study British Journal of Cancer, October 23, 2014    Clinical Article

20 The effect of deployment to a combat zone on testosterone levels and the association with the development of posttraumatic stress symptoms: A longitudinal prospective Dutch military cohort study Psychoneuroendocrinology, October 23, 2014    Clinical Article

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Clinical Pearls in Nurse Practitioner

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Highlights in Nurse Practitioner

Calcium reduces CRC risk

As reported in the International Journal of Cancer, there is an 8% reduction in CRC risk with each 300 mg/d increase in calcium intake based on 15 studies involving 12305 patients who took 250-1900 mg of calcium/day over a 3.3-16 year follow-up period. The beneficial effect extended beyond 1000 mg/d.

Pre-operative tranexamic acid reduces blood loss in ovarian cancer patients

As reported in ACTA Obstetricaet Gynecologica, a single pre-operative dose of tranexamic acid (15 mg/kg) significantly reduced blood loss (520 cc vs 730 cc) and the transfusion rate (30% vs. 44%) in ovarian cancer patients (n=100) undergoing radical debulking.

Low vitamin D associated with statin-induced myalgia

As reported in Clinical Therapeutics, of 450 patients prescribed high-dose simvastatin (80 mg qd) for dyslipidemia, 11.1% complained of myalgias. The vitamin D level was lower in patients with myalgias than patients without myalgias (26.2 vs. 36.3 ng/mL).

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