Hospital readmission rate in patients discharged on parenteral antibiotics
As reported in Clinical Infectious Diseases, the hospital readmission rate for patients (n=782) discharged on parenteral antibiotics was 26%. The mean patient age was 58 years. The leading diagnoses were bacteremia, osteomyelitis, and pyelonephritis. The indications for readmission included non-infection related (30%), worsening symptoms (29%), and new infections (19%). The ORs for readmission factors were as follows: each decade increase in age, 1.09; aminoglycoside use, 2.33; resistant organism, 1.57; and number of hospital discharges in prior 12 months, 1.20.
Relationship benefit in women with IHD
As reported in BMC Medicine, women who were married or living with a partner had a decreased risk of mortality (RR=0.72) after the first ischemic heart disease (IHD) event compared to women who were not married or living with a partner. The study involved 734626 women with no history of IHD who were followed for 8.6 y; there were 30747 women with a first IHD event and 2148 deaths.
Lecithinized superoxide dismutase treatment promising in idiopathic interstitial pneumonia
As reported in BMC Pulmonary Medicine, lecithinized superoxide dismutase (80 mg x 28d) attenuated LDH and surfactant protein A levels in patients with progressive idiopathic interstitial pneumonia; there was no change in forced vital capacity. The LDH and surfactant protein levels returned to baseline by day 56. There were no differences between adverse events and mortality rates in the treated and placebo groups.