Trends in drug-resistant tuberculosis in a gold-mining workforce in South Africa, 2002-2008
The International Journal of Tuberculosis and Lung Disease, 06/22/2012
van Halsema CL et al. – Despite decreasing TB notifications overall, multidrug–resistant TB (MDR–TB) notifications and proportions of episodes with MDR–TB increased in the larger company. Cure must be ensured in first episodes to prevent acquired resistance. Improved coverage of culture, drug susceptibility testing and human immunodeficiency virus testing is required to allow treatment to be optimised.