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Clinical parameters in male genital lichen sclerosus: a case series of 329 patients
Journal of the European Academy of Dermatology and Venereology, 06/12/2012
Edmonds EVJ et al. – Male genital lichen sclerosus (MGLSc) is unequivocally a disease of the uncircumcised male; the adult peak is late in the fourth decade; dyspareunia is a common presenting complaint; non–specific histology requires careful interpretation; most men are either cured by topical treatment with ultrapotent steroid (50–60%) or by circumcision (>75%); effective and definitive management appears to abrogate the risk of developing penile squamous cell carcinoma; urinary contact is implicated in the pathogenesis of MGLSc; HPV infection and autoimmunity seem unimportant.