Ethnic Differences in Skin Physiology, Hair Follicle Morphology and Follicular Penetration
Skin Pharmacology and Physiology, 05/24/2012
Luther N et al. – Whereas no significant differences with regard to skin physiological parameters could be observed, morphological analysis of the hair follicles revealed, inter alia, that Caucasians had significantly larger terminal hair follicles than Asians and Africans. The surface of the hair follicle infundibulum was shown to be 3% in Caucasians, 2.6% in Africans and 2.4% in Asians. The investigations into penetration revealed no significant differences after a 30–min penetration time, whereas after 24 h, the Asian volunteers presented significantly larger amounts of sodium fluorescein in the hair follicles and the stratum corneum, which may be explained by cultural habits.