Pretherapeutic uracil and dihydrouracil levels of colorectal cancer patients are associated with sex and toxic side effects during adjuvant 5-flurorouracil-based chemotherapy
Cancer, 04/19/2012
Clinical Article
Wettergren Y et al. – Pretherapeutic Ura and UH2 levels per se may be related to risk of side effects during adjuvant 5–fluorouracil (5–FU)–based treatment, whereas the UH2/Ura ratio may not always reveal such a risk. Sex is a strong risk factor for toxicity, showing the importance of evaluating male and female patients separately.



