Proactive and integrated primary care for frail older people: Design and methodological challenges of the Utrecht Primary care PROactive Frailty Intervention Trial (U-PROFIT)

BMC Geriatrics, 05/16/2012

In a large, pragmatic trial conducted in daily clinical practice with frail older patients, several challenges and methodological issues will occur. Recruitment and retention of patients and feasibility of the interventions are important issues. To enable broad generalizability of results, careful choices of the design and outcome measures are required.

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