Calcium homeostasis may influence resting energy expenditure with effects most apparent in early pubertal girls

Hanks LJ et al. – Decreased calciotropic hormone levels along with increased related nutrient intakes were associated with greater resting energy expenditure (REE), although these relationships differed according to adiposity. The physiologic response to the diet and subsequent energy partitioning needs to be considered in the context of puberty. In particular, regulation and signalling of the calciotropic network during pubertal maturation warrant investigation.

Methods

• Thirty-six girls aged 7–11 years participated. REE was assessed by indirect calorimetry, and body composition, dietary intake (calcium, vitamins D and K, phosphorus) and serum hormones (PTH, osteocalcin, 25OHD) were evaluated by DXA, 24 h recall and serum assay, respectively.

Results

• A positive association between vitamin K and REE and an inverse association of parathyroid hormone (PTH) with REE (p = 0.05) were observed. PTH and REE were positively related in those having normal adiposity (p = 0.03) and inversely related in those with excess adiposity (p = 0.01).
• The association of REE with vitamin K intake was evident in lean individuals (p = 0.001), but was null in those with excess adiposity.

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