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Below you will find bonus content hand-picked by our senior medical editor, D. Scott Cunningham, MD, Ph.D, as well as clinical pearls derived from our Internal Medicine Review. All this plus more, free with your membership.
Increased incidence of second primary cancers in patients with salivary gland tumors
As reported in JAMA—Otolaryngology-Head & Neck Surgery, patients with salivary gland tumors have an increased risk of second primary tumors and newly developed cancers. Specifically, the cumulative 2-, 5-, and 10-year rates for second primary cancers are 4.4%, 8.3%, and 12.4%, respectively. Similarly, the cumulative 2-, 5-, and 10-year rates for newly diagnosed cancers are 1.1%, 3.4%, and 10.5%, respectively.
CHD7 associated with survival in pancreatic ductal adenocarcinoma patients receiving gemcitabine
As reported in Cancer Research, low CHD7 expression is associated with increased RFS and OS in pancreatic ductal adenocarcinoma patients receiving gemcitabine. There was no association between CHD7 expression and RFS or OS in patients who were not treated with gemcitabine.
Asenapine effective in treating agitation
As reported in Acta Psychiatrica Scandinavica, treatment of agitation with sublingual asenapine (10 mg) was shown to be effective. Improvement in the PANSS-EC was comparable to the effect of intramuscular anti-psychotics.