NP Medical News about Sodium Bicarbonate Contrast-Induced Nephropathy

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Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
Annals of Internal Medicine, 11/03/09

Zoungas S et al. – This review of 9 published and 14 unpublished trials of sodium bicarbonate suggests that the effect of this agent has been overestimated. Unpublished trials found smaller effects than published trials, and formal testing confirmed publication bias. Sodium bicarbonate is probably less effective at preventing contrast–induced nephropathy than is currently thought. Routine use of sodium bicarbonate for prevention of contrast–induced nephropathy is therefore premature.

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Efficacy of Single-Bolus Administration of Sodium Bicarbonate to Prevent Contrast-Induced Nephropathy in Patients With Mild Renal Insufficiency Undergoing an Elective Coronary Procedure
The American Journal of Cardiology, 10/01/09 Relevance Score: 88%

Sodium Bicarbonate for the Prevention of Contrast Induced-Acute Kidney Injury: A Systematic Review and Meta-analysis
Clinical Journal of the American Society of Nephrology, 10/07/09 Relevance Score: 81%

Iloprost Prevents Contrast-Induced Nephropathy in Patients With Renal Dysfunction Undergoing Coronary Angiography or Intervention
Circulation, 10/23/09 Relevance Score: 65%

A comparative study of ceruminolytic agents
Indian Journal of Otolaryngology and Head & Neck Surgery, 10/07/09 Relevance Score: 65%

Acid-Base Balance in Peritoneal Dialysis Patients: A Stewart-Fencl Analysis
Renal Failure, 10/29/09 Relevance Score: 64%