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See Latest ArticlesPediatric cholesteatoma and variants in the gene encoding connexin 26
The Laryngoscope, 11/03/09
James AL et al. – GJB2 gene variants are present in a minority of children with cholesteatoma, but may be more common than in normal populations. It is conceivable that alterations of connexin 26 expression could contribute to the multifactorial disease process in cholesteatoma by modifying the cell–to–cell communication that is important in proliferation and migration of keratinocytes.
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