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See Latest ArticlesCross-species models of OCD spectrum disorders
Psychiatry Research, 10/28/09
Boulougouris V et al. – Several axis–I neuropsychiatric disorders are characterised by repetitive motor habits suggestive of underlying inhibitory dyscontrol, and may constitute members of a putative obsessive–compulsive (OC) spectrum. Notable examples include obsessive–compulsive disorder (OCD) and trichotillomania (repetitive hair–pulling). Multiple tiers of evidence link these conditions with underlying dysregulation of fronto–striatal circuitry and monoamine systems. These abnormalities represent key targets for existing and novel treatment interventions.
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