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See Latest ArticlesRapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors
Pediatric Blood & Cancer, 10/30/09
Lam C et al. – Tuberous sclerosis complex is associated with hamartomatous growths including subependymal giant cell astrocytomas. Since chemo–radiation therapies offer scant benefit, oncologists had traditionally been little involved in managing SEGAs. Recent evidence demonstrating rapamycin efficacy in adults and children with TSC–associated tumors foresee a practice change.
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