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Cutaneous Lupus Erythematosus: Issues in Diagnosis and Treatment
American Journal of Clinical Dermatology, 10/20/09

Walling HW et al. – Treatments for cutaneous LE initially include preventive (e.g. photoprotective) strategies and topical therapies (corticosteroids and topical calcineurin inhibitors). For skin disease not controlled with these interventions, oral antimalarial agents (most commonly hydroxychloroquine) are often beneficial. Additional systemic therapies may be subdivided into conventional treatments (including corticosteroids, methotrexate, thalidomide, retinoids, dapsone, and azathioprine) and newer immunomodulatory therapies (including efalizumab, anti–tumor necrosis factor agents, intravenous immunoglobulin, and rituximab).

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