NP Medical News about Fasciitis, Necrotizing

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Necrotizing fasciitis
Canadian Family Physician, 10/14/09

Puvanendran R et al. – Necrotizing fasciitis is a rare but potentially fatal disease; it can occur in all parts of the body, including the oral cavity and the perineum.

Typically, patients who develop type 1 (polymicrobial) necrotizing fasciitis are immunocompromised in some way. However, with the type 2 (monomicrobial) variety, patients are usually immunocompetent with a history of trauma (sometimes minor).
Diagnosis is often delayed because of a paucity of signs and a low index of suspicion.
Necrotizing fasciitis is a clinical diagnosis. Blood tests and imaging, especially magnetic resonance imaging and computed tomography scans, can be helpful but are not diagnostic. Surgical exploration is advised if clinical suspicion is high.
Management includes fluid resuscitation, if indicated, intravenous broad spectrum antibiotics, and early surgical debridement. Increasingly, community–acquired methicillin–resistant Staphylococcus aureus is being identified as the infective agent.

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Monomicrobial necrotizing fasciitis in a white male caused by hypermucoviscous Klebsiella pneumoniae
Journal of Medical Microbiology, 10/21/09 Relevance Score: 68%

A very extensive necrotizing fasciitis
Annales Françaises d'Anesthésie et de Réanimation, 10/30/09 Relevance Score: 67%

Necrotizing fasciitis in a patient with overlap syndrome of systemic sclerosis and systemic lupus erythematosus
Rheumatology International, 11/16/09 Relevance Score: 66%

Hyperbaric oxygen therapy as an anti-infective agent
Expert Review of Anti-infective Therapy, 10/21/09 Relevance Score: 64%

The Conundrum of the Gram-Positive Rod: Are We Missing Important Pathogens in Complicated Skin and Soft-Tissue Infections? A Case Report and Review of the Literature
Surgical Infections, 10/08/09 Relevance Score: 62%