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Nutritional related liver disease: targeting the endoplasmic reticulum stress
Current Opinion in Clinical Nutrition & Metabolic Care, 10/23/09
Kammoun HL et al. – Endoplasmic reticulum (ER) stress has been recently involved in the development of hepatic steatosis. Thus, ER stress could represent in the future an eligible therapeutic target for the treatment of nonalcoholic fatty liver disease. However, as ER stress is a fundamental mechanism involved in cell survival, any modification of this pathway must be carefully assessed.
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