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Allergic Reactions and Risk of Vulvodynia
Annals of Epidemiology , 10/13/09
Harlow BL et al. – An altered immuno–inflammatory response to environmentally induced allergic reactions may predispose women to the development of vulvodynia or may be markers of an already heightened immuno–inflammatory response.
Methods- The authors studied 239 women with and 239 women without vulvodynia to assess the influence of self–reported allergic reactions antecedent to first development of vulvar pain symptoms among cases, and a matched reference age among controls.
- Women with self–reported hives prior to first report of vulvar pain or reference age among controls were 2.5 times more likely to develop vulvodynia.
- Those reporting a history of allergic reactions to insect bites were 2.1 times more likely, and those reporting a history of seasonal allergies were 2.0 times more likely to develop vulvodynia.
- Findings were similar in a restricted subset of clinically confirmed cases and matched controls.
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