NP Medical News about Analgesics patches Defibrillators

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Analgesic patches and defibrillators: a cautionary tale
Europace, 10/09/09

Brown MR et al. – Implantable cardioverter defibrillator (ICD) insertions have increased significantly over the last decade. Transdermal patches are increasingly used for drug delivery. Skin burns associated with metal containing transdermal patches have been reported with magnetic resonance imaging and external cardiac defibrillation. However, there are no reports of dermal injury secondary to an ICD shock and a transdermal drug delivery patch. The authors report the first known case of a patient who suffered a dermal burn following a defibrillation due to a transdermal patch being positioned over the ICD.

Exclusive Author Commentary
Martin R. Brown, 10/12/09

This case demonstrates the need for awareness when placing metal containing patches. There was no warning contained in the product information and so patients, and medical and nursing staff need to be trained to site them away from the ICD generator.

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Utilization characteristics and treatment persistence in patients prescribed low-dose buprenorphine patches in primary care in the United Kingdom: A retrospective cohort study
Clinical Therapeutics, 10/09/09 Relevance Score: 67%

Factors associated with a continuous regular analgesic use - a population-based study of more than 45 000 Danish women and men 18-45 years of age
Pharmacoepidemiology and Drug Safety, 10/01/09 Relevance Score: 47%

Co-analgesics - today and tomorrow - A receptor-based overview of therapeutical options
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 11/17/09 Relevance Score: 45%

Use of analgesic and sedative drugs in the NICU: integrating clinical trials and laboratory data
Pediatric Research, 11/09/09 Relevance Score: 45%

Efficacy and Side Effects of Diclofenac Patch in Treatment of Patients with Myofascial Pain Syndrome of the Upper Trapezius
Journal of Pain and Symptom Management, 10/13/09 Relevance Score: 45%