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See Latest ArticlesThe skinny on fat: lipolysis and fatty acid utilization in adipocytes
Trends in Endocrinology and Metabolism, 10/16/09
Ahmadian M et al. – Lipolysis for the provision of fatty acids (FA) for other organs during times of energy demand occurs uniquely in white adipose tissue (WAT). Recent findings have identified a bona fide TAG hydrolase and the major adipose phospholipase A2, AdPLA. By controlling PGE2 levels, AdPLA dominantly regulates lipolysis in an autocrine/paracrine manner. Here, the authors discuss the regulation of lipolysis and its effects on FA utilization within WAT and on insulin resistance.
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