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See Latest ArticlesForward genetics used to identify new gene Mon1a with critical role in controlling macrophage iron metabolism and iron recycling from erythrocytes
Nutrition Reviews, 09/30/09
McCreedy RA et al. – Cell–based studies showed that Mon1a is necessary for vesicular trafficking of proteins, including the iron–export protein ferroportin, to the macrophage cell membrane. The forward genetics approach, which has currently only been used sparingly by the nutrition research community, offers a powerful and unbiased approach to identifying genes important in nutritional metabolism.
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