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New views on the hypothesis of respiratory cancer risk from soluble nickel exposure; and reconsideration of this risks historical sources in nickel refineries
Journal of Occupational Medicine and Toxicology, 08/24/09

Heller JG et al. – Epidemiological methods have failed to accurately identify the source(s) of observed lung cancer risk in at least one nickel refinery (KNR). This failure, together with the negative long–term animal inhalation studies on soluble nickel and other toxicological evidence, strongly suggest that the designation of soluble nickel as carcinogenic should be reconsidered, and that the true causes of historical lung cancer risk at certain nickel refineries lie in other exposures, including insoluble nickel compounds, arsenic, sulphuric acid mists and smoking.

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