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Diesel exhaust causing low-dose irritant asthma with latency?
Occupational Medicine, 08/25/09
Adewole F et al. – Fifteen workers were identified with occupational asthma attributed to diesel exhaust. Three had validated new–onset asthma with latency. All worked in bus garages where diesel exhaust exposure was the only likely cause of their occupational asthma. Occupational asthma was confirmed by measures of non–specific reactivity and serial measurements of PEF with Oasys scores of 2.9, 3.73 and 4. The known non–specific irritant effects of diesel exhaust suggest that this is an example of low–dose irritant–induced asthma and that exposures to diesel exhaust in at least some bus garages are at a sufficient level to cause this.
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