Your Article Summary
See Latest ArticlesThe use of triiodothyronine as an augmentation agent in treatment-resistant bipolar II and bipolar disorder NOS
Journal of Affective Disorders, 06/22/09
Kelly T et al. - A high percentage of bipolar II and bipolar NOS patients with treatment resistant depression improved on T3. Despite the use of higher than usual doses in many of the patients, the medication was well tolerated. Augmentation with supraphysiologic doses of T3 should be considered in cases of treatment resistant bipolar depression.
Methods- Retrospective chart review of patients treated in a private clinic between 2002 and 2006.
- The charts of 125 patients with bipolar II disorder and 34 patients with bipolar disorder NOS were reviewed.
- Patients had been unsuccessfully treated with an average of 14 other medications before starting T3.
- At an average dose of 90.4 mcg (range 13 mcg–188 mcg) the medication was well tolerated.
- None of the patients experienced a switch into hypomania, and only 16 discontinued due to side effects.
- Improvement was experienced by 84%, and 33% experienced full remission.
Related Articles
Safety and Efficacy of Quetiapine in Bipolar Depression
Annals of Pharmacotherapy, 10/13/09
Relevance Score: 67%
Mecamylamine ? a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders
Expert Opinion in Pharmacotherapy, 11/02/09
Relevance Score: 64%
Bipolar Disorder Patient Care Opportunities: Let's Answer the Call
Annals of Pharmacotherapy, 10/16/09
Relevance Score: 46%
Subgenual cingulate volumes in offspring of bipolar parents and in sporadic bipolar patients
European Archives of Psychiatry and Clinical Neuroscience, 10/13/09
Relevance Score: 46%
Sodium Load Combined with Low Doses of Exogenous Angiotensin II Upregulate Intrarenal Angiotensin II
Kidney and Blood Pressure Research, 10/08/09
Relevance Score: 46%
Today in Mental Health...keeping you current
Receive free subspecialty "5-minute updates" via email
Preventing depression in high-risk groups
Current Opinion in Psychiatry, 12/04/09
Decreasing pediatric patient anxiety about radiology imaging tests: prospective evaluation of an educational intervention
Journal of Child Health Care, 12/04/09
Change in delusions is associated with change in jumping to conclusions
Psychiatry Research, 12/04/09