Your Article Summary
See Latest ArticlesRapid correction of low vitamin D status in nursing home residents
Osteoporosis International, 06/20/08
Przybelski R et al. – This prospective study finds that ergocalciferol 50,000 IU three times weekly for four weeks effectively and safely corrects vitamin D inadequacy in nursing home residents.
Methods- Study to evaluate the efficacy and safety of short course, high dose, oral vitamin D2 (ergocalciferol) treatment
- 63 nursing home residents were enrolled
- The 25 with low vitamin D status received oral ergocalciferol 50,000 IU x3 weekly for 4 wks; the others received no change to their routine care
- Serum total 25(OH)D, 25(OH)D2, 25(OH)D3, calcium, parathyroid hormone (PTH), bone turnover markers and neuro-cognitive assessments were obtained at baseline and 4 wks
- Mean total 25(OH)D concentration increased from 17.3 to 63.8 ng/ml in the treated group and remained unchanged in the comparison group
- Serum 25(OH)D3 remained stable in the comparison group, but declined with D2 treatment from 15.4 to 9.1 ng/ml
- Serum PTH trended down in the treatment group
- No treatment-induced improvement in ambulation, cognition or behavior was observed
- No hypercalcemia or other adverse effects were observed with ergocalciferol treatment
Related Articles
Vitamin D Deficiency/Insufficiency Practice Patterns in a Veterans Health Administration Long-Term Care Population: A Retrospective Analysis
Journal of the American Medical Directors Association, 11/12/09
Relevance Score: 89%
Vitamin D and mortality in older men and women
Clinical Endocrinology, 10/16/09
Relevance Score: 89%
Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials
British Medical Journal, 10/09/09
Relevance Score: 84%
Recognition and Management of Vitamin D Deficiency
American Family Physician, 10/19/09
Relevance Score: 83%
Vitamin D supplementation in older persons: benefits and requirements
Aging Health, 10/07/09
Relevance Score: 83%
Today in Geriatrics...keeping you current
Receive free subspecialty "5-minute updates" via email
A review of heart failure management in the elderly population
The American Journal of Geriatric Pharmacotherapy, 12/18/09
Vardenafil for the treatment of erectile dysfunction: an overview of the clinical evidence
Clinical Interventions in Aging, 12/18/09
Burden of chronic obstructive pulmonary disease in medicare beneficiaries residing in long-term care facilities
The American Journal of Geriatric Pharmacotherapy, 12/18/09