Tiotropium bromide for chronic obstructive pulmonary disease
Mamary AJ et al. - Tiotropium is associated with increased lung function, health-related quality of life and exercise tolerance, and reduced dyspnea and acute exacerbations of COPD. It has been hypothesized that tiotropium may retard the accelerated decline in lung function associated with COPD. Tiotropium is safe and well-tolerated, with few side effects. Herein, the authors discuss the pharmacology, physiology and safety profile of tiotropium, as well as the clinical studies that have demonstrated its efficacy in COPD. [more...]
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