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Alpha-Adrenergic Receptor Antagonists in Older Patients With Benign Prostatic Hyperplasia: Issues and Potential Complications
Fine SR et al. - The article discusses the role of non–subtype-selective and subtype-selective 1-adrenergic receptor antagonists in the clinical management of BPH. Safety and tolerability for both non–subtype-selective and subtype-selective 1-adrenergic receptor antagonists for patients with BPH are also reviewed. [more...] Internal Medicine 07/24/08
Influence of the Level of Renal Insufficiency on Endoscopic Changes in the Upper Gastrointestinal Tract Stolic R et al. - In patients with end stage renal disease, endoscopic lesions of the gastrointestinal tract are detected less frequently in relation to patients without kidney disease. [more...] Internal Medicine 07/24/08
PRAME expression and clinical outcome of breast cancer Epping MT et al. – Expression of the tumor antigen PReferentially expressed Antigen of MElanoma (PRAME) is a prognostic marker for clinical outcome of breast cancer, independent of traditional clinicopathological markers [more...] Oncology 07/24/08
Identification of claudin-4 as a marker highly overexpressed in both primary and metastatic prostate cancer Landers KA et al. – Claudin-4 may be a useful potential marker and therapeutic target for prostate cancer (PCa), metastases based on its prominent expression in both primary and secondary PCas and its established role as a receptor for Clostridium perfringens enterotoxin [more...] Oncology 07/24/08
The Role of Carotid Plaque Vulnerability and Inflammation in the Pathogenesis of Acute Ischemic Stroke Ding S et al. - The results suggest that inflammation plays a crucial role in carotid plaque vulnerability and, together with carotid plaque morphology, in the pathogenesis of acute ischemic stroke. [more...] Internal Medicine 07/24/08
Masculinity and the Body: How African American and White Men Experience Cancer Screening Exams Involving the Rectum Winterich JA et al. - Regardless of race or education, men experienced DREs more negatively than colonoscopies because penetration with a finger was associated with a gay sexual act. Some men disliked colonoscopies, however, because they associated any penetration as an affront to their masculinity. [more...] Family Medicine 07/24/08
Adding fresh frozen plasma to rituximab for the treatment of patients with refractory advanced CLL Klepfish A et al. - Adding FFP to RTX may provide a useful therapeutic option in patients with advanced CLL resistant to treatment. [more...] Internal Medicine 07/24/08
Cardiovascular Risk After Bariatric Surgery for Obesity Batsis JA et al. - The test studies confirmed the directionality of CV risk, with estimated relative risk reductions for bariatric surgery patients ranging from 18% to 79% using the Framingham risk score compared with 8% to 62% using the PROCAM risk score. In conclusion, bariatric surgery predicts long-term decreases in CV risk in obese patients. [more...] Cardiology 07/24/08
Impact of immediate vs delayed axillary node dissection on surgical outcomes in breast cancer patients with positive sentinel nodes: results from American College of Surgeons Oncology Group Trials Z0010 and Z0011 Olson JA et al. - In a trial to examine the impact of the timing of completion axillary lymph node dissection (cALND) on pathologic results and complications in pts with breast cancer metastasis to the sentinel lymph nodes (SLNs), it was found that LN recovery and long-term complications were similar after either delayed or immediate cALND for these pts. Pts who undergo immediate cALND experience more short-term morbidity. There is no clear detriment for pts with a positive SLN who undergo a second procedure for cALND [more...] Oncology 07/24/08
Beliefs about common health problems and work: A qualitative study Barnes MC et al. - Beliefs were relatively consistent across geographical locations, although changes in forms of work and social structure of communities were more salient issues within the ex-coalfield areas. Care needs to be taken that initiatives aimed at reducing incapacity for work due to CHPs do not simply add to the pressure to ‘be well’. [more...] Family Medicine 07/24/08
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