Neurology Medical News about Clarithromycin Ketamine

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Clarithromycin, a potent inhibitor of CYP3A, greatly increases exposure to oral S-ketamine
European Journal of Pain, 11/10/09

Hagelberg NM et al. – Oral ketamine is used as an adjuvant in the treatment of refractory neuropathic and cancer–related pain. Drug interactions may alter the analgesic or other effects of ketamine...Clarithromycin strongly increases plasma concentrations of oral S–ketamine probably by inhibiting its CYP3A–mediated N–demethylation. This increase is reflected as modest changes in behavioral effects of oral S–ketamine.

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Use of oral ketamine in chronic pain management: A review
European Journal of Pain, 11/02/09 Relevance Score: 47%

Gamma and Delta Neural Oscillations and Association with Clinical Symptoms under Subanesthetic Ketamine
Neuropsychopharmacology, 11/10/09 Relevance Score: 44%

Clarithromycin–Amoxycillin-Containing Triple Therapy: A Valid Empirical First-Line Treatment for Helicobacter pylori Eradication in Hong Kong
Helicobacter, 11/09/09 Relevance Score: 43%

A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Hysterectomy
Anesthesia & Analgesia, 10/21/09 Relevance Score: 43%

Analysis of Clarithromycin Resistance and CagA Status in Helicobacter pylori Using Feces from Children in Thailand
Journal of Clinical Microbiology, 10/08/09 Relevance Score: 43%