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The 5-HT1B Receptor: A Novel Target for the Pathophysiology of Depression
Current Drug Targets, 11/03/09

Ruf BM et al. – A review of the literature provides strong evidence that 5–HT1B receptors and related factors such as p11 are involved in the pathophysiology of depression. The following explores possible factors which may render the 5–HT1B receptor dysfunctional, resulting in susceptibility to depression. Implications of using the 5– HT1B receptor as a biomarker for vulnerability to MDD are discussed.

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Predictors of depression in a multiethnic cohort of patients with rheumatoid arthritis
Arthritis Care and Research, 11/03/09 Relevance Score: 95%

Survival after myocardial infarction worse with first episode major depression than recurrent major depression
Evidence-Based Mental Health, 11/02/09 Relevance Score: 95%

Quality of life and depression among metastatic breast cancer patients
Medical Oncology, 10/05/09 Relevance Score: 95%

Serious diabetes-specific emotional problems in patients with type 2 diabetes who have different levels of comorbid depression: A Polish study from the European Depression in Diabetes (EDID) Research Consortium
European Psychiatry, 11/06/09 Relevance Score: 94%

A systematic review of longitudinal studies on the association between depression and smoking in adolescents
BMC Public Health, 10/01/09 Relevance Score: 94%