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Postdural Puncture Headache in Complex Regional Pain Syndrome: A Retrospective Observational Study
Pain Medicine, 10/29/09
Munts AG et al. – A high incidence (76%) and prolonged course (median 18 days, range 2 days to 36 months) of postdural puncture headache (PDPH) was found. Radionuclide studies performed in two patients with long–lasting symptoms (12–16 months) did not reveal cerebrospinal fluid (CSF) leakage. In patients without signs of CSF leakage (N = 38), epidural blood patches administered in 24 patients were effective in 54%, while ketamine infusions administered in six patients were effective in 67%. These observations may suggest that other mechanisms besides intracranial hypotension play a role in the initiation and maintenance of PDPH in CRPS and stimulate new directions of research on this topic.
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