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Tiede W et al. – The authors propose, that sleep reduction leads to an impairment of activation in the ascending pathway (leading to reduced LEPs). In contradistinction, pain perception was boosted, which the authors attribute to lack of pain control distinct from classical descending inhibition, and thus not affecting the projection pathway. Sleep–restricted subjects exhibit reduced attentional modulation of pain stimuli and may thus have difficulties to readily attend to or disengage from pain.

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