Neurology Medical News about Cardiomyopathy, Hypertrophic

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High Prevalence of Abnormal Nocturnal Oximetry in Patients With Hypertrophic Cardiomyopathy
JACC - Journal of the American College of Cardiology, 10/28/09

Eleid MF et al. – Abnormal nocturnal oximetry is common in patients with HCM, suggesting that OSA is prevalent. OSA may impact hemodynamics and symptoms in HCM. Further studies are needed to determine the long–term benefit of OSA treatment on hemodynamics and disease progression in HCM.

Exclusive Author Commentary
Mackram F. Eleid, 10/29/09

Our study's discovery that nighttime oxygen desaturations are common in patients with hypertrophic cardiomyopathy raises the importance of screening for obstructive sleep apnea in this patient population. Patients with symptoms from hypertrophic cardiomyopathy despite optimal medical therapy may experience benefit from treatment of their sleep apnea which could possibly decrease the need for septal reduction therapy (surgery or alcohol septal ablation), which some patients with hypertrophic cardiomyopathy ultimately require.

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Electrocardiographic amplitudes: a new risk factor for sudden death in hypertrophic cardiomyopathy
European Heart Journal, 11/10/09 Relevance Score: 68%

Severe Left Ventricular Wall Thinning and Extensive Fibrosis Without Evolution to End Stage Disease in a Patient With Hypertrophic Cardiomyopathy
Journal of The American Society of Echocardiography, 10/12/09 Relevance Score: 67%

Cell Cycle Re-Entry and Mitochondrial Defects in Myc-Mediated Hypertrophic Cardiomyopathy and Heart Failure
PLoS ONE - Cardiovascular Disorders, 10/02/09 Relevance Score: 67%

Severe Hypertrophic Cardiomyopathy in an Infant with a Novel PRKAG2 Gene Mutation: Potential Differences Between Infantile and Adult Onset Presentation
Pediatric Cardiology, 10/02/09 Relevance Score: 67%

Diagnostic accuracy of extended-length electrocardiogram in differentiating between athlete's heart and hypertrophic cardiomyopathy
Journal of Electrocardiology, 10/29/09 Relevance Score: 66%