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Western blot analysis for the detection of serum antibodies recognizing linear Aquaporin-4 epitopes in patients with Neuromyelitis Optica
Journal of Neuroimmunology, 10/26/09
Marnetto F et al. – The high sensitivity and specificity of the western blot assay in detecting serum anti–AQP4 antibodies in NMO patients suggest that such auto–antibodies may be of linear nature, thus recognizing epitopes that are displayed in denatured protein.
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