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Milone M et al. – The authors report two HIV–negative SLONM/monoclonal gammopathy patients who improved following intravenous immunoglobulin (IVIg) treatment alone or in combination with immunosuppressant agents. This favorable response to treatment suggests that a dysimmune mechanism is operative in some SLONM individuals. They suggest that IVIg deserves initial consideration for SLONM therapy.



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