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Subgenual Prefrontal Cortex Activity Predicts Individual Differences in Hypothalamic-Pituitary-Adrenal Activity Across Different Contexts
Biological Psychiatry, 10/23/09
Jahn AL et al. – The findings suggest that activation in subgenual PFC may be related to HPA output across a variety of contexts (including familiar settings and novel or threatening situations). Individuals prone to elevated subgenual PFC activity across multiple contexts may be individuals who consistently show heightened cortisol and may be at risk for stress–related HPA dysregulation.
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