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Current Challenges in Glia-Pain Biology
Neuron, 10/22/09

McMahon SB et al. – A remarkable series of findings over the last decade or so has demonstrated a previously unrecognized role for CNS glia in many aspects of neuronal functioning including pain processing. In addition to their recruitment to sites of CNS damage, these cells also appear to be capable of “action at a distance,” playing functional roles in areas of CNS that are quite remote from the focus of injury or disease. The implication is that the nervous system is able to initiate signals that alter the function of these glial cells, and these cells in turn release factors that regulate neuronal function. This idea has taken root, resulting in an explosion of research interest, and here the authors look critically at what has been reported in order to assess where knowledge is missing or uncertain.

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The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: A cross-sectional study
Arthritis Research & Therapy, 11/03/09 Relevance Score: 49%

Pain among Veterans of Operations Enduring Freedom and Iraqi Freedom: Do Women and Men Differ?
Pain Medicine, 10/13/09 Relevance Score: 49%

Prognosis for patients with chronic low back pain: inception cohort study
British Medical Journal, 10/09/09 Relevance Score: 49%

Characterization of chronic pain patients in German pain centers. Core data from more than 10,000 patients
Schmerz, 10/06/09 Relevance Score: 49%

Corticosteroid Injection Treatment to the Ischiadic Spine Reduced Pain in Women With Long-Lasting Sacral Low Back Pain With Onset During Pregnancy: A Randomized, Double Blind, Controlled Trial
Spine, 10/01/09 Relevance Score: 49%