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Innate but not adaptive immune responses contribute to behavioral seizures following viral infection
Epilepsia, 11/02/09
Kirkman NJ et al. – The authors have implicated the innate immune response to viral infection, specifically TNF–alpha and IL–6, and concomitant inflammatory changes in the brain as contributing to the development of acute seizures. This model is a potential infection–driven model of mesial temporal lobe epilepsy with hippocampal sclerosis.
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