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See Latest ArticlesGenetic Association Analysis between TDP-43 Polymorphisms and Alzheimer's Disease in a Japanese Population
Dementia and Geriatric Cognitive Disorders, 10/23/09
Shibata N et al. – Although none of the SNPs showed statistically significant association, the authors identified an association between a specific haplotype (G-A-A-G) of the TDP-43 gene and risk for AD. They could not confirm any synergetic association between the SNPs and APO E in their AD patients. Despite the relatively small sample size, these results indicate a possible genetic association between TDP- 43 and AD
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