Neurology Articles

Neurology

sponsor
Become a Member Today!
Register
Email:


Password:

Remember me
Forgot your Password?
Invite Code?
Article ID

Your Article Summary

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Ohara PT et al. – Neurons in sensory ganglia are surrounded by satellite glial cells (SGCs) that perform similar functions to the glia found in the CNS. When primary sensory neurons are injured, the surrounding SGCs undergo characteristic changes. There is good evidence that the SGCs are not just bystanders to the injury but play an active role in the initiation and maintenance of neuronal changes that underlie neuropathic pain. In this article the authors review the literature on the relationship between SGCs and nociception and present evidence that changes in SGC potassium ion buffering capacity and glutamate recycling can lead to neuropathic pain–like behavior in animal models. The role that SGCs play in the immune responses to injury is also considered. The authors propose the term gliopathic pain to describe those conditions in which central or peripheral glia are thought to be the principal generators of principal pain generators.

Related Articles

Dissecting the functional significance of endothelin A receptors in peripheral nociceptors in vivo via conditional gene deletion
Pain, 11/02/09    Relevance Score: 68%

T-Cell Recognition of Prostatic Peptides in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome
The Journal of Urology, 10/14/09    Relevance Score: 68%

Effect of peritoneal fluid from endometriosis patients on neuroblastoma cells in culture
Gynecological Endocrinology, 10/29/09    Relevance Score: 67%

Current Challenges in Glia-Pain Biology
Neuron, 10/22/09    Relevance Score: 67%

Satellite tumors surrounding primary pleomorphic adenomas of the parotid gland
European Archives of Oto-Rhino-Laryngology, 11/09/09    Relevance Score: 66%

Today in Pain Medicine...keeping you current

How Humans Integrate the Prospects of Pain and Reward during Choice
Journal of Neuroscience, 11/25/09

Post-infectious new daily persistent headache may respond to intravenous methylprednisolone
The Journal of Headache and Pain, 11/25/09

Is insufficient quantity and quality of sleep a risk factor for neck, shoulder and low back pain? A longitudinal study among adolescents
European Spine Journal, 11/25/09


Sponsor

Article Search

Keyword:

Search:

Published within

Sort By:
Date
Relevance


Sponsor

Send this Summary to a Colleague

Enter email address