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See Latest ArticlesCentral nervous system effects of alcohol at a pseudo-steady-state concentration using alcohol clamping in healthy volunteers
British Journal of Clinical Pharmacology, 10/23/09
Zoethout RWM et al. – Most CNS effects of alcohol showed a trend to change over time, despite stable concentrations. Other variables remained stable under pseudo–steady–state conditions. The intravenous clamping method provides precise control over BrAC levels and allows frequent repetition of different CNS measurements. These features make this technique eminently suitable to study the complex pharmacodynamic effects of acute alcohol administration.
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