Neurology Medical News about Pain Stroke Deep Brain Stimulation

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Analgesia in conjunction with normalisation of thermal sensation following deep brain stimulation for central post-stroke pain
Pain, 10/16/09

Pickering AE et al. – The authors report the case of a 56–year–old man, who, following a temporo–parietal infarct, suffered from debilitating and refractory hemi–body cold dysaesthesia and severe tactile allodynia. This was associated with thermal and tactile hypoaesthesia and hypoalgesia on his affected side. Implantation of a deep brain stimulating electrode in his periventricular gray (PVG) region produced an improvement in his pain that was associated with a striking normalisation of his deficits in somatosensory perception. This improvement in pain and thermal sensibility was reversed as stimulation became less effective, because of increased electrode impedance. Therefore, the authors postulate that the analgesic benefit may have occurred as a consequence of the normalisation of somatosensory function and the authors discuss these findings in relation to the theories of central pain generation and the potential to engage useful plasticity in central circuits.

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