Neurology Medical News about Neuralgia Glial Cell Line-Derived Neurotrophic Factor

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. 2008 Exclusive Survey—Earnings: Good news for primary care income

3. Medicare pay-for-reporting effort draws fire from frustrated doctors

4. Debunking Myths in the US Healthcare System

5. Doctors and the DEA Free full text

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Modulation of Neuropathic Pain by a Glial-Derived Factor
Pain Medicine, 10/14/09

Adler JE et al. – Intrathecal application of GDNF stimulates expression of somatostatin, a neuropeptide with potential analgesic properties. Moreover, stimulation of dorsal root sensory neurons with GDNF in vitro increases cell content of somatostatin, which, in turn, leads to increased secretion in response to depolarizing stimuli. The authors suggest that GDNF exerts its anti–allodynic effect via somatostatinergic mechanisms. These observations suggest new approaches for treating nerve injury that may prove useful in preventing delayed complications that contribute to long–term debility.

<< Previous
Interpretation Bias for Ambiguous Social Behavior Among...

Next >>
Voltage-Gated Sodium Channels: Therapeutic Targets for Pain

Effects of Neurotrophic Factors on Growth and Glial Cell Alignment of Cultured Adult Spiral Ganglion Cells
Audiology & Neuro-Otology, 10/23/09 Relevance Score: 93%

Glial cell line-derived neurotrophic factor (GDNF) and its receptors in human ovaries from fetuses, girls, and women
Fertility and Sterility, 11/11/09 Relevance Score: 92%

Cell-Specific Inducible Gene Recombination in Postnatal Inner Ear Supporting Cells and Glia
Journal of the Association for Research in Otolaryngology, 10/14/09 Relevance Score: 81%

Neural differentiation of periodontal ligament stem cells induced by neurotrophic Schwann cells factors
Archives of Medical Science, 11/02/09 Relevance Score: 80%

The signaling pathway leading to ERK5 activation via G-proteins and ERK5-dependent neurotrophic effects
Molecular Pharmacology, 11/04/09 Relevance Score: 79%