Neurology Medical News about Neuroblastoma

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Recent Advances in Targeted Anti-Vasculature Therapy: The Neuroblastoma Model
Current Drug Targets, 10/23/09

Pastorino F et al. – Several reports have been published concerning the relationship between tumour progression and angiogenesis in experimental models of neuroblastoma in vitro and in vivo. Moreover, a high vascular index in neuroblastoma correlates with poor prognosis, suggesting dependence of aggressive tumour growth on active angiogenesis.

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Integrated genomic profiling identifies two distinct molecular subtypes with divergent outcome in neuroblastoma with loss of chromosome 11q
Oncogene, 11/12/09 Relevance Score: 89%

Microtubule-associated Protein-2 is a Sensitive Marker of Primary and Metastatic Neuroblastoma
American Journal of Surgical Pathology, 10/28/09 Relevance Score: 88%

Targeting of HDAC8 and investigational inhibitors in neuroblastoma
Expert Opinion on Investigational Drugs, 10/12/09 Relevance Score: 88%

Decreased aortic growth and middle aortic syndrome in patients with neuroblastoma after radiation therapy
Pediatric Radiology, 10/05/09 Relevance Score: 88%

Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells
Molecular Cancer, 10/02/09 Relevance Score: 88%