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Ros-mediated activation of NF-kB and Foxo during muscle disuse
Muscle & Nerve, 10/22/09
Dodd SL et al. – The increased catalase activity abolished immobilization–induced transactivation of both NF–kB and Foxo and attenuated the loss of muscle mass. Thus, H2O2 may be an important initiator of these signaling pathways that lead to muscle atrophy.
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