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Ybarra J et al. – Simple and efficient screening methods are lacking for diabetic peripheral neuropathy (DPN), the most common and most difficult to treat of the long–term diabetic complications. Increased levels of transforming growth factor beta 1 (TGFbeta1) in type 2 diabetic patients (T2DM) plays an immunomodulatory role in diabetic nephropathy and, possibly, in atherosclerotic evolution. TGFbeta1 stands as an important biomarker molecule for DFN and DPN screening in the series. Further prospective studies are warranted.


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