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Alpha7 neuronal nicotinic receptors: The missing link to understanding Alzheimer's etiopathology
Medical Hypotheses, 10/08/09
Bencherif M et al. – The convergence of beta–amyloid deposition and/or ApoE4 binding and co–localization with alpha7 NNRs, which are favored under conditions of low cholinergic tone, and the downstream cascade of tau hyperphosphorylation through disinhibition of GSK–3beta appear to explain and reconcile many of the discordant findings in this very active area of CNS research.
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Today in Dementia...keeping you current
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Behavioural and psychological symptoms in vascular dementia; differences between small and large vessel disease
Journal of Neurology, Neurosurgery, and Psychiatry , 12/11/09
Behavioral Dimensions and Acetylcholinesterase Inhibitor-related Effect in Alzheimer Disease Over Time: A Latent Trajectory Modeling
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Disturbances in Everyday Life Activities and Sequence Disabilities in Tool use for Alzheimer Disease and Vascular Dementia
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